"As an industrial designer who uses a computer a lot of the time, I have also experienced sweaty hands on a mouse. I personally believe that the Zephyr pro mouse is a good and useful design when it comes to operating or spending time on your pc for a long period. The air directed to the palm of your hand as you operate the mouse is great. However, The openings/holes will let in more dust meaning cleaning regularly will be a job that comes with owning one of these. What happens if the user spills liquid over the mouse? But otherwise, I like the concept."